Obese with higher FNDC5/Irisin levels have a better metabolic profile, lower lipopolysaccharide levels and type 2 diabetes risk
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چکیده
منابع مشابه
Paradoxical Lower Serum Triglyceride Levels and Higher Type 2 Diabetes Mellitus Susceptibility in Obese Individuals with the PNPLA3 148M Variant
BACKGROUND Obesity is highly associated with elevated serum triglycerides, hepatic steatosis and type 2 diabetes (T2D). The I148M (rs738409) genetic variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is known to modulate hepatic triglyceride accumulation, leading to steatosis. No association between PNPLA3 I148M genotype and T2D in Europeans has been reported. Aim of this s...
متن کاملleptin levels in obese and non-obese african and caucasian subjects with type 2 diabetes
it has previously been demonstrated that circulating levels of leptin show ethnic differences when controlled for the confounding influence of adiposity. this study examined leptin levels in non-obese and obese subjects with type 2 diabetes of african versus caucasian origin. materials and methods non-obese and obese subjects with type 2 diabetes of either african origin living in dar es salaam...
متن کاملLipid Profile and Leptin Levels in Patients with Metabolic Syndrome
Abstract Background and Objective: Metabolic syndrome called a cluster of several metabolic disorders is associated with increased risk of cardiovascular diseases. Genetic differences in leptin receptor gene are related with the concentration and activity of leptin in that these discrepancies can influence lipid levels. We aimed to determine the association between the leptin receptor gene p...
متن کاملAssessment of Vitamin D3 Levels and Metabolic Profile in Pre-diabetic and Type 2 Diabetes Mellitus Patient of Kanpur City- A Cross Sectional Study
Objective: It has been explored that Vitamin D play role in various non-skeletal disorders including Diabetes Mellitus. The present study was designed with the aim to assess association among control, pre-diabetic and diabetic with vitamin D and association between lipid profile and vitamin D. Materials and Methods: A total of 109 subjects were recruited for the cross-sectional study including...
متن کاملHigher Intraocular Pressure Levels Associated With Lower Hysteresis In Type 2 Diabetes
Methods: One hundred eyes of 100 subjects (between the ages of 17-91) who applied to Adnan Menderes University’s Ophthalmology Clinic between January-March 2015 were included in this study, 50 diabetics (Group 1) and 50 healthy controls (Group 2). The eyes included in the study were randomly chosen. Corneal Hysteresis (CH), Corneal Resistance Factor (CRF), Goldmann correlated Intraocular Pressu...
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ژورنال
عنوان ژورنال: Archives of Endocrinology and Metabolism
سال: 2017
ISSN: 2359-4292,2359-3997
DOI: 10.1590/2359-3997000000305